Differential effect of aqueous Desmodium gangeticum root extract mediated TiO 2 nanoparticles on isolated mitochondria, cells and Wistar rats

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A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract

Many challenges are associated with the oral delivery of insulin, relating to the physical and chemical stability of the hormone, and its absorption and metabolism in the human body. The present study aims to demonstrate the oral delivery of insulin in both normal and steptozotocin (STZ)-induced diabetic rats with the help of the aqueous extract of Desmodium gangeticum (DG) root. Human insulin ...

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Cardiotonic and Anti Ischemic Reperfusion Injury Effect of Desmodium Gangeticum Root Methanol Extract

Objectives: Anti ischemic reperfusion effect of crude methanol extract of Desmodium gangeticum root had been reported earlier but how is modulating its cardiotonic effect to render cardio-protection is largely unknown. Methods: The inotropic effect of methanol extract of Desmodium gangeticum root was investigated on isolated frog heart and further analyzed the physiological and biochemical effe...

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Administration of aqueous extract of Desmodium gangeticum (L) root protects rat heart against ischemic reperfusion injury induced oxidative stress.

Myocardial reperfusion is believed to be associated with free radical injury. The present study evaluates the effect of aqueous extract of D. gangeticum (DG) on lipid peroxides and antioxidants in ischemic reperfused (IR) Wistar albino male rats. Significant elevation in lipid peroxide products (thiobarbituric acid reactive substances) and decreased activity of antioxidant enzymes (superoxide d...

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Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury

The present study investigate the protective effect of aqueous root extract of Desmodium gangeticum in preserving mitochondrial and sarcoplasmic ATPase during ischemia reperfusion injury. The isolated rat hearts in both drug and control group were subjected to warm ischemia (37°), followed by reperfusion with the Langendorff perfusion system. The aqueous root extract of Desmodium gangeticum (L)...

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ژورنال

عنوان ژورنال: Asian Pacific Journal of Tropical Biomedicine

سال: 2017

ISSN: 2221-1691

DOI: 10.1016/j.apjtb.2017.09.020